Tamoxifen is one of the best SERM (Selective Estrogen Receptor Modulator) products on the market and a very popular Sopharma product used by athletes who use steroids. Tamox is an antagonist and an agonist at the same time, acting as an estrogen in some parts of the body and an anti-estrogen in other parts of the body. What determines its action to protect against gynecomastia and activate the production of its own testosterone by normalizing lipid levels, reducing the possibility of atherosclerotic changes.
You can buy Tamoxifen easily and comfortably in our store.
Mechanism of action
Tamoxifen citrate is in fact a nonsteroidal estrogen receptor blocker that exhibits strong antiestrogenic properties, but it is actually a receptor modulator. Tamoxifen is effective in inhibiting efficient binding of estradiol to estrogen receptors, preventing exposure to a specific receptor by blocking the DNA response to estrogen exposure. The result is a reduction in the activity of the corresponding genes, which lowers the cell's response to estrogen. In addition, an estrogen antagonist increases the regulation of W-protein (TGFb) production, which prevents the development of cancer cells, and also reduces the level of insulin-like growth factor 1 (IGF-1), which reduces the division of all cells. including cancer cells. Tamoxifen further reduces the activity of the PKC enzyme and, depending on the dose,
Therefore, buying tamoxifen reduces the chance of developing various types of cancer.
Tamoxifen actually has many application methods when it comes to steroid cycles for high level athletes.Due to its wide range of actions, tamoxifen therapy is mostly used by targeted bodybuilders in steroid cycles or later as post cycle therapy. First, the action of tamoxifen prevents the estrogen-related side effects of steroids. Tamoxifen blocks release receptors in breast tissue, preventing the development of gynecomastia (breast development in women).
- Blocks estrogen receptors,
- Normalizes the lipid profile, which reduces the possibility of developing atherosclerosis,
- Reduces the risk of breast cancer by 50%,
- Reduces the risk of osteoporosis (bone fragility),
- Activates the production of LH and FSH, increasing the level of endogenous testosterone, so it is used as a PCT drug,
- It can be used to combat gynecomastia,
The consumption of this drug is individual and for different uses.
For example, to quickly stop the onset of gynecomastia, it is recommended that you take 40 mg of tamoxifen per day until the severity of gynecomastia symptoms subsides.
As a PCT product, tamoxifen is often used in doses of 20-40 mg per day, depending on the "" severity "" of the steroid cycle for 3-4 weeks in the context of taking chorionic gonadotropin 2000 U every other day ( if gonadotropin was not used in the cycle itself, supporting the work of the testicles).
It is important to clarify that it is not recommended to take tamoxifen in case of consumption of steroids such as nandrolone, trenbolone or mibolerone, due to the possible increase in the side effects of the progestin.