Boldenone (Equipoise) is a potent anabolic steroid with the active chemical boldenone undecylenate, first synthesized in the 1950s, it was developed exclusively for veterinary needs (from cows to dogs). However, this has not prevented athletes from all over the world from successfully using this drug in bodybuilding and other sports, thanks to its beneficial effect on metabolism, stimulating protein synthesis and increasing the number of red blood cells.
On the black market, boldenone undecylenate is known under the following brand names:
The steroid profile of the drug:
- Androgenic index: 50
- Anabolic index: 100
- Estrogenic activity: low
- Progestin activity: very low
- Half life: 2 weeks
- Liver toxicity: none.
- Preparation form: injection
- The withdrawal period of the drug: 4-5 months
The main effects of the drug:
- Helps to gain mass (in combination with other steroids), accelerates protein synthesis
- stimulates the appetite
- Dry the muscles, make it sooth
- Increases vascularity
- Improves endurance performance (as a result of accelerating oxygen transport to the muscles)
History of the discovery of boldenone and pharmaceutical companies.
In 1949, the Swiss pharmaceutical company Ciba boldenone patented it as a synthetic anabolic steroid.In the early 1950s and 1960s, the company actively conducted scientific experiments in search of boldenone esters, and in the late 1960s and early 1970s it finally succeeded in creating a boldenone undecylenate ester that worked at long-term, which began to be sold under the brand name Parenabol (meaning drug injection), which has been used medicinally for muscle hypertrophy and protection of bones from destruction in osteoporosis.
At the end of the 1970s, boldenone definitively disappeared from the pharmacological market and appeared a few years later, already on the veterinary market (mainly used to increase muscle mass in horses), under the brand name Equipoise thanks to the American biopharmaceutical company Squibb, which sold this drug until the end of 1985.
In 1985, the Belgian chemical company Solvay buys boldenone from Squibb and sells it on its behalf until 1995, which is then taken over by another American pharmaceutical company, Wyeth (later transformed into the veterinary company Fort Dodge Animal Health"), which still sells equilibrium to America and other countries of the world.
Currently, many generics (drugs that have identical active ingredients to those patented) of boldenone undecylenate have appeared on the market, which means that all patents on the drug have already expired.
Boldenone and animals
As you already understood, there are a few trade names for this drug, all of which are united by the active ingredient boldenone undecylenate. So, as we said earlier, boldenone was previously used exclusively in animal husbandry (to increase the appetite and increase the weight of animals):
- Equipoise (USA) for horses
- Ganabol (Colombia) for cows and other horned pets
- Venobol (Germany) for chickens
- Ganabol (veterinary boldenone)Despite this, athletes, especially western ones, use boldenone a lot in their physical training, because this drug has a strong anabolic effect, moderately androgenic and well tolerated by the body.
The Connection Between Boldenone and Other Anabolic Steroids
It is no secret that many anabolic steroids, in their chemical structure and action on the human body, are very similar. Let's compare the popular anabolic steroids (Methandrostenolone, Testosterone, and Nandrolone) with Boldenone in more detail.
Boldenone and methane
Once upon a time, many (even pharmacology specialists!) mistakenly believed that boldenone undecylenate (hereafter boldenone) is an injectable analogue of the popular steroid methandrostenolone, due to their similarity in chemical structure.
If we remove the methyl group in the seventeenth position of Dianabol and the ether chain in the same position in boldenone, then in both cases these drugs will have identical chemical formulas, it has been this fact, for a long time, that has misled many people. .
This is so, but the methyl group in the seventeenth position has a strong effect on the final properties of the drug, changing its spatial structure of the molecule. After methandrostenolone has passed through the liver 2-3 times! the methyl group in the seventeenth position is cleaved and the "methane" becomes 17-methyl-estradiol and the boldenone molecule, with the same cycle, becomes the weaker estradiol, the whole process of cleavage and transformation takes place under the influence of * aromatase.
* Aromatase is an adrenal enzyme that converts androgens (male sex hormones) into estrogen.
Therefore, the differences will be the following:
The degree of aromatization (the conversion of testosterone to estradiol, a substance with estrogenic properties) of boldenone is much lower than that of "methane".
Unlike boldenone, methandrostenolone cannot activate the androgen receptor archive (due to the methyl group)
Methandrostenolone 100 tablets (anabolic steroids)
As you can see, these are not the same drugs, but completely different, and they only have one thing in common: to stimulate the appetite, which is why both drugs are so popular during the period of mass gain.
Boldenone and Testosterone
The boldenone undecylenate molecule also has a similar structure to the testosterone molecule, the only difference is in the presence of an additional double bond (ring A), which is why boldenone is considered a universal drug, because it is not subject to the action. of the enzyme 5-alpha reductase, and this is the human enzyme responsible for the conversion of testosterone to dihydrotestosterone (DHT).
5-alpha-reductase is a human enzyme involved in steroidogenesis, that is, the biological process in which steroids are formed from cholesterol and its subsequent transformation into other steroids.
That is, it turns out that 5-alpha-reductase radically changes the properties of the original substance, but as you read above, it has no effect on boldenone, so this drug is considered universal, regardless of who takes it.
The chemical formula of testosterone.
The following general links emerge between boldenone and testosterone:
Both substances perfectly stimulate the androgen receptor and have non-genomic activity (increase in the number of nuclei in existing muscle fibers).
However, even at high doses, boldenone, unlike testosterone, does not affect IGF-1 (insulin-like growth factor) production by muscle fibers.
boldenone and nandrolone
In their effect on the human body, both drugs have the greatest similarity (despite molecular differences), mainly in the activation time of the androgen receptor and in the tendency to aromatization.
The aromatization in nandrolone, that is, the conversion to estradiol, occurs without the participation of the aromatase enzyme.
The identical properties of both drugs, administered to humans, have misled many experts, according to which nandrolone and boldenone are two interchangeable drugs. However, this is not entirely true, first of all, because nandrolone is converted under the action of the enzyme 5-alpha reductase into dihydrotestosterone, which is in many respects inferior to testosterone in terms of androgen receptor activity in the tissue. muscle, while the 5-alpha reductase in boldenone has no effect, so boldenone can rightfully be considered a powerful nandrolone steroid.
Balkan Pharmaceuticals Nandrolone
And of course, don't forget that nandrolone, unlike boldenone, generally lacks non-genomic activity. But on the other hand, the first drug is more successful in terms of weight gain, mainly due to the active ability to stimulate progesterone receptors (progestin activity). This is why boldenone is often used with methandriol dipropionate, allowing it to catch up with nandrolone in terms of mass gain.
Very often, athletes who use nandrolone in their training change it in the second half of the course to boldenone undecylenate, which is gentler on the body, not so much because it suppresses the production of endogenous testosterone, but because it is testosterone, which is produced by the body independently of cholesterol.
Features of the application and other properties of boldenone.
when you gain weight
Athletes use boldenone quite successfully during the "mass gain" period, that is, when it is important to increase muscle mass without thinking about its quality. However, at first glance, it may seem that the use of this drug for weight gain is not entirely reasonable, since it is not subject to aromatization and does not have progestin activity. This is why when Boldenone is taken for mass gaining purposes, it is combined with “long-acting” testosterone such as enanthate or cypionate.
When using boldenone (equipoise), it increases appetite, which of course has a positive effect on weight gain, however, as many experienced "chemists" know from their practice, to achieve a good result, boldenone must be combined with medicinal products in which the concentration of the active ingredient is 200 mg/ml.
boldenone for weight gain
Many pharmacological experts recommend using boldenone when drying out muscles because it works well.
The almost complete absence of aromatization and progestin activity prevents excess water from accumulating in the body.
However, remember the increased appetite for boldenone when you use it to dry yourself.
Boldenone to dry muscle mass
Effect of boldenone on resistance
Boldenone affects the number of red blood cells (erythrocytes), there is more due to the stimulation of one of the kidney hormones, erythropoietin, which increases due to an increase in metabolites 5b.
This property of boldenone, such as an increase in the number of red blood cells, is successfully used by athletes in various sports, in particular, aerobic orientation, where endurance plays a decisive role. For bodybuilders, this property of boldenone will also be useful, since, with the growth of muscle mass, the capillary network in the muscles also increases and, of course, we must not forget about the venosity, which will be up to the task. use this drug, and this is not an irrelevant factor for bodybuilders who perform in competition.
Boldenone for resistance development
How fast does boldenone work?
Due to the heavy and long ether chain, boldenone does not immediately (slowly) affect the body and remains in the blood for about 3-4 weeks. Another disadvantage of boldenone is the fact that 1/3 of the drug does not work "ballast".
The obvious disadvantages of boldenone undecylenate led pharmacological laboratories to synthesize the substances boldenone acetate and boldenone propionate, which are distinguished by a longer period of action and rapid inclusion in the work. In addition, both substances (boldenone acetate and propionate) are not without drawbacks, as many athletes point out, they are very painful, and they are not used much in bodybuilding, which cannot be said for other sports where resistance is the predominant factor. . (athletics, skiing, cycling, etc.).
What dose of boldenone should be used?
The optimal dose is in the range of 300-800mg per week, and for low Boldenone doses (300mg) to be effective, it makes sense to combine them with other anabolic steroids. A working dose for an athlete is around 600-800mg per week.
The long half-life of boldenone (the time during which half of the drug is eliminated from the body after the first injection, that is, the concentration of ether in the blood is reduced by 2 times) allows you to give injections no more than once. once a week However, pharmacological specialists recommend increasing the dose by 1.5 to 2 times in the first 2 weeks, due to the slow activation of this drug.
Boldenone should not be injected more than once a week, in addition to the risk of increased side effects in the body, you can quickly achieve a cumulative effect (enhanced action).
To prevent girls from having irreparable side effects in the form of virilization (male hair growth and deepening of voice in the first place) after using boldenone, we recommend reducing the dosage to 75-100mg per week and duration. of the course should not exceed 4-5 weeks.
With which steroids can Boldenone be combined (used)?
To increase muscle mass, Boldenone is combined with injections of Sustanon or Testosterone Enanthate. Also, you can add oxymetholone to this pack.
For a more pronounced "mass gain" effect, boldenone can also be used with methandriol dipropionate, while due to methandriol's short half-life of 2-3 days, its injections should be given at intervals: 2 ml -1 every 2 days or 3 ml 1 time in 3 days. Additionally, testosterone can also be added to the combination of boldenone and methandriol to speed up weight gain.
To dry out the muscles, boldenone is usually used in conjunction with trenbolone or stanozolol, some combine all three drugs, which is also acceptable in principle.
More experienced athletes can try the combination of Boldenone + Testosterone Propionate to improve muscle quality and relief.
Courses and working dosages of boldenone (equipoise)
The duration of the course of work for men is 8-10 weeks, with the optimal dose of boldenone 400-800 mg per week (1 time), all that is lt, 400 mg is ineffective, and all that is>, 800 mg does not lead to the best result. on the contrary, it increases the risk of side effects.
Boldenone Work Courses
To gain muscle mass, the balance is perfectly combined with trenbolone and testosterone (in this case, we reduce the course to 6 weeks, so as not to suppress the production of our testosterone, and be sure to take antiestrogens)
For relief and dryness of muscles, Boldenone combines well with Anavar and Winstrol
And, of course, do not forget that not only strength training associated with the use of anabolic steroids is involved in the enhanced process of muscle growth, but also elemental nutrition (for drying, for mass), which is also a powerful anabolic factor in increasing muscle mass and strength
Bulking Steroid Course (Boldenone + Testosterone Enanthate)
We present you one of the most popular, proven and effective “chemistry” courses for beginners, for which you need to buy the following on the “black market”:
- Provide 200 or 250 mg/mL
- Testosterone Enanthate 250mg/ml
- Tamoxifen 10 mg tablets
- Anastrozole (1 mg/form) or Letrozole (2.5 mg/form)
Thanks to the inclusion of boldenone in the course, we reduce the dose of testosterone enanthate to minimum values without prejudice to the anabolic effect, in addition, this combination allows to reduce the internal conversion of anabolic steroids into estrogens and the androgenic activity of the course. .
Tamoxifen, Anastrozole, reduces the level of aromatization of anabolic steroids, which helps minimize side effects caused by high levels of estrogen in the blood.
Approximate Weight Course for Expert “Chemical Athletes”:
- Week 1-8: Equipoise 800mg/week (reduce to 400-600mg to start)
- Weeks 1-8: Testosterone Enanthate 500 mg/week
- Weeks 1-10: anastrozole or letrozole as determined by estradiol test
- Week 11-13: Tamoxifen 20 mg per day
- Week 14: Tamoxifen 10 mg per day
Equipoise has low aromatization, so testosterone injections are proportionally less prone to it, for example if boldenone is set to 400/600, testosterone is correspondingly 600/800.
Steroid course for muscle relief and dryness (Boldenone + Testosterone Propionate + Winstrol)
To complete this course, we need the following pharmacological drugs:
- Boldenone 200mg/ml
- Testosterone Propionate 100mg/ml
- Winstrol 50mg/ml (or tablets)
- Anastrozole (1 mg/form) or Letrozole (2.5 mg/form)
- Tamoxifen 20 mg tablets
The inclusion in the course of Winstrol will provide you with a set of high-quality lean muscles and it will look like this:
- Week 1-8: Equipoise 800mg/per week
- Weeks 1 8: Testosterone Propionate 100 mg/ml every other day
- Week 6-10: Winstrol 50 mg/day (or 10-20 mg daily, in tablets)
- Weeks 1-10: anastrozole or letrozole as determined by estradiol test
- Week 11-13: Post-course therapy with tamoxifen
Boldenone Course for Muscle Relief
The dose of testosterone and boldenone can be reduced, and sometimes should be reduced, if you start to have health problems.
Always remember, the higher the dosage value, the higher the possibility of side effects in the body.
Side Effects of Boldenone (Equipoise)
Boldenone does not have a significant effect on the production of its own testosterone, due to resistance to the enzyme 5-alpha reductase, as well as the inability to convert into a potent androgen, dihydrotestosterone, therefore such side effects (prostatic hypertrophy, acne, baldness, growth of body and facial hair, etc.) due to androgenic activity, the balance is obviously not observed with its correct use (only applies to men).
In addition, we note that the low estrogenic activity file of boldenone (2 times lower than that of testosterone!), allows athletes to use it in their training without the use of any antiestrogens that protect the athlete from gynecomastia, edema and hypertension at the same time. time, balanced in the athlete's body, it acts as an aromatase inhibitor, which inhibits the conversion of testosterone to estrogen, so be sure to monitor the level of estradiol (so that it does not slide to zero).
Ongoing Anabolic Steroids for Acne
Due to an increase in the level of erythrocytes, the rheological properties of the blood may deteriorate, that is, the hematocrit (the volume of red blood cells, reflecting the ratio of erythrocytes to plasma) will increase, so it is important to check hematocrit in the course of boldenone, in case of deviation from the norm, consult a doctor, as a rule, renal or pentoxifylline is prescribed, which will prevent aggregation (adhesion) of erythrocytes, that is, will not allow the creation of « columns of coins” and their three-dimensional conglomerates in whole blood, thus improving the rheology of the blood.
Some athletes, when using boldenone, report acne on the arms, shoulders, chest and back, which is quite easily removed by applying special hygienic lotions and using antimicrobial soaps.
For women, balance is one of the safest anabolic steroids, mainly due to its low androgenic activity (the risk of virilization phenomena will be minimal).
Of course, don't forget your lipid profile: anabolic steroid use raises your LDL (bad) cholesterol level, so make sure you're using omega-3 fatty acid supplements in a "chemistry" of course, and get tested. hormone test.
If we analyze the reviews on the use of boldenone, it becomes clear that this drug has proven to be very effective, both separately when taken and in combination with other anabolic steroids.
Athletes note that if you take boldenone in the recommended doses, there are practically no side effects (except acne), but the anabolic effect is quite noticeable (depending on the course combination, muscle mass / muscle relief / endurance gradually increases).
Many trainers recommend using Equipoise as the first anabolic steroid, mainly due to its pronounced anabolic effect on the body and low androgenic effect.
Among the negative aspects of boldenone is its rather high price, which prevents many athletes from using it in their training.